In 2025, Sanofi pursued a series of strategic collaborations, acquisitions, and licensing agreements aimed at strengthening its core franchises, expanding its pipeline, and positioning the company for long-term growth. These deals reflect a targeted approach to innovation, focusing on high-value therapeutic areas such as immunology, oncology, rare diseases, and vaccines.
One of the year’s major moves was the acquisition of Astellas’ rare disease portfolio, which added late-stage and commercial-stage assets in neuromuscular and metabolic disorders. This strengthened Sanofi’s leadership in rare diseases and expanded its pipeline in areas with significant unmet need.
Sanofi also entered a strategic partnership with TScan Therapeutics to co-develop T-cell receptor-based therapies for oncology. This collaboration provides access to innovative immuno-oncology platforms while complementing Sanofi’s existing cancer therapy portfolio, accelerating its presence in next-generation treatments.
In vaccines, Sanofi signed a licensing and collaboration deal with Moderna to co-develop mRNA-based influenza and combination vaccines. This deal positions Sanofi to leverage mRNA technology for faster, more effective vaccine development and broadens its capacity for innovative public health solutions.
Additionally, a strategic alliance with Precision BioSciences focused on genome editing technologies, aiming to advance therapies in immunology and rare diseases. This agreement underscores Sanofi’s commitment to adopting cutting-edge modalities that can transform patient care.
Strategic Impact and Outlook
Collectively, these deals reflect Sanofi’s focused approach to pipeline diversification, innovation acceleration, and global expansion. By combining internal R&D with external expertise, Sanofi has enhanced its ability to deliver next-generation therapies while mitigating development risk.
Looking ahead, these strategic partnerships and acquisitions are expected to:
- Accelerate development of high-potential therapies in oncology, immunology, rare diseases, and vaccines.
- Strengthen competitive positioning by integrating innovative technologies and platforms.
- Expand global patient access to advanced treatments.
- Support long-term sustainable growth, reinforcing Sanofi’s strategy of combining operational discipline with scientific leadership.
Sanofi’s 2025 deal activity positions the company to maintain momentum in 2026 and beyond, delivering transformative solutions to patients while reinforcing its leadership across therapeutic areas with significant unmet need.


