Key Highlights:
- CMS launches WISeR, a 6-state pilot starting January 2026, deploying artificial intelligence and machine learning to speed prior authorization for 17 high-risk procedures, aiming to curb fraud and waste in traditional Medicare.
- Final clinical coverage decisions remain with licensed human reviewers, yet critics warn AI-driven systems could raise denial rates and delay care, potentially impacting patient safety and satisfaction.
- The model marks a significant move to modernize traditional Medicare administration while provoking industry debate over transparency, equity, and future regulatory standards.
AI-Powered Prior Authorization: New Model and Scope
CMS’s WISeR (Wasteful and Inappropriate Service Reduction) program introduces AI prior authorization for select procedures—including tissue substitutes, electrical nerve-stimulator implants, and knee arthroscopy—across Arizona, New Jersey, Ohio, Oklahoma, Texas, and Washington. The technology, partnered with direct provider submissions or post-service review, is designed for services historically prone to fraud or excessive use.
Operational Impact and Safeguards
Artificial intelligence and machine learning will streamline processing, with CMS emphasizing that all denial decisions must receive licensed clinician review. Inpatient, emergency, and high-risk delay services are excluded to preserve patient safety. Traditional Medicare currently averages one prior authorization per 100 enrollees—a fraction compared to Medicare Advantage plans.
Stakeholder Concerns and Criticisms
Advocates and experts caution that profit incentives for claim reviewers, coupled with AI’s potential for errors and opaque logic, could increase denial rates and administrative burden. Senate investigations reveal AI denial rates outpace manual ones by a factor of sixteen, raising fears about care access for vulnerable populations. Civil rights groups demand explicit protections against algorithmic bias, calling CMS’s current rules “a missed opportunity” for equity.
Industry Perspective and Future Outlook
CMS frames WISeR as a path to care navigation and value-based reimbursement, with AI expected to cut waste and speed approvals. Yet regulatory bodies and organizations like CTeL urge rigorous oversight, more rulemaking on AI bias and discrimination, and transparent accountability for automated coverage decisions. The pilot’s success and scalability will likely influence broader Medicare modernization and adoption of AI across U.S. healthcare in coming years.





